Skip to content

For laboratory research use only — not for human or veterinary use

Compound comparison

GHK-Cu vs GHK

Same tripeptide backbone, one key difference: GHK-Cu carries a chelated copper(II) ion, while GHK is the free peptide without copper. The copper is what most copper-peptide research is built around. Supplied for laboratory research use only; not for human or veterinary use.

GHK-Cu GHK
Form Copper-bound tripeptide complex Free tripeptide
Copper (Cu²⁺) Yes — chelated No
Peptide sequence Gly-L-His-L-Lys + copper Gly-L-His-L-Lys
Molecular formula C14H22CuN6O4 C14H24N6O4
Molecular weight ≈ 402 Da ≈ 340.4 Da
PubChem CID 165429100 73587
Primary research area Tissue, dermatology & biomaterials Copper-peptide chemistry (base peptide)
Format at TagPep 100 mg lyophilized research vial Reference only — not stocked

Molecular data verified against PubChem. CAS (49557-75-7) is applied to both forms across sources, so it is omitted here in favour of unambiguous identifiers.

What the copper changes

GHK is the bare tripeptide (glycyl-histidyl-lysine). GHK-Cu is that peptide chelated to a copper(II) ion. The bound copper is integral to the copper-peptide research the complex is studied in, and it shifts the molecular weight from ≈340 Da to ≈402 Da. When a study or product specifies "GHK-Cu," the copper complex is what is intended.

Research context

GHK-Cu is a characterized reference material in tissue, dermatology and biomaterials research, with identity and reported purity confirmed by batch documentation. See the GHK-Cu research guide and the research-peptide reference table.

GHK-Cu 100 mg — in stock

Copper-bound tripeptide · lyophilized research vial with batch documentation

View product

Free GHK is listed for reference only. Browse the full catalog in the shop, or see how to choose a supplier.

Common questions

What is the difference between GHK-Cu and GHK?

GHK is the free tripeptide glycyl-L-histidyl-L-lysine. GHK-Cu is that same tripeptide chelated to a copper(II) ion. The bound copper is the defining difference and is integral to most copper-peptide research; it also changes the molecular formula and weight (≈402 Da for the complex vs ≈340 Da for the free peptide). Both are supplied for laboratory research use only.

Does GHK-Cu contain copper and GHK does not?

Yes. GHK-Cu is the copper-bound complex (a copper(II) ion chelated to the GHK tripeptide). GHK refers to the peptide on its own, without copper. The CAS number 49557-75-7 is applied to both forms across different sources, so identity is best confirmed by formula, molecular weight and batch documentation rather than CAS alone.

Can I buy GHK-Cu for research?

Yes. TagPep stocks GHK-Cu as a 100 mg lyophilized research vial with batch-specific analytical documentation, for laboratory research use only. The free GHK peptide is shown here for reference and comparison.

Research-use notice

Factual reference information for laboratory research and educational use. Both compounds are research materials supplied for laboratory research use only — not for human or veterinary use, consumption, injection, administration, diagnosis, or treatment. No dosing or administration guidance is provided or implied.